SCHEMBL4153935

SCHEMBL4153935

NC(=O)CCC(C(N)=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 9/20 0.55
CHRM2 P08172 6/20 0.55
KCNH2 Q12809 2/20 0.55
LMNA P02545 1/20 0.55
CYP2D6 P10635 1/20 0.55
CHRM1 P11229 1/20 0.55
KDM4E B2RXH2 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
OPRM1 P35372 2/20 0.45
DRD3 P35462 2/20 0.45
DRD2 P14416 1/20 0.45
HTT P42858 1/20 0.43
SLC22A2 O15244 1/20 0.43
SLC22A1 O15245 1/20 0.43
PGR P06401 1/20 0.43
THRB P10828 1/20 0.43
ADRB3 P13945 1/20 0.43
OPRK1 P41145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4138872 0.91 CHRM3 (0.54) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL10596455 0.87 CHRM3 (0.51) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL1769745 0.87 CHRM3 (0.51) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL4146916 0.87 CHRM3 (0.51) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL10524246 0.82 CHRM3 (0.57) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL7550538 0.81 CHRM3 (0.44) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL10392372 0.81 CHRM3 (0.55) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL27963558 0.81 CHRM3 (0.55) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL9295790 0.81 CHRM3 (0.59) CHRM3CHRM2KCNH2LMNACYP2D6
SCHEMBL7102456 0.81 MAPT (0.47) CHRM3CHRM2KCNH2LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN claimed
CN-116425904-A Supported Ziegler-Natta catalyst and preparation method and application thereof 山东京博石油化工有限公司 2023-07-14 CN disclosed
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES BASF SE (DE) 2009-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131657-A1 PROCESS FOR ALKENYLATING CARBOXAMIDES PRMT5, CYC1, CBR3 CHRM3 797/4885CHRM2 695/4885KCNH2 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.