SCHEMBL10524397

SCHEMBL10524397

Cc1ccc(OC(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.41
BCHE P06276 1/20 0.37
GPR3 P46089 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
TEAD4 Q15561 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.34
CA2 P00918 2/20 0.34
AR P10275 1/20 0.34
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
RELA Q04206 1/20 0.33
TP53 P04637 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10177249 0.94 ACHE (0.39) ACHEBCHEGPR3CYP3A4TSHR
SCHEMBL13802538 0.87 ACHE (0.34) ACHEBCHEGPR3CYP3A4TSHR
SCHEMBL4549523 0.86 ACHE (0.44) ACHEBCHEGPR3CYP3A4TSHR
SCHEMBL12200950 0.80 ACHE (0.42) ACHEBCHEGPR3CYP3A4TSHR
SCHEMBL9578601 0.78 ESR2 (0.42) CYP3A4ALDH1A1MAPTMEN1KMT2A
SCHEMBL1119552 0.78
SCHEMBL1258083 0.78 TRPV1 (0.40) CA2CA1CA9
SCHEMBL28943132 0.78 CA1 (0.42) TSHRALDH1A1CA2CA1CA9
SCHEMBL13613395 0.77 ACHE (0.35) ACHEBCHEGPR3TP53
SCHEMBL24871286 0.77 ACHE (0.44) ACHEBCHEGPR3CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1135737-A None JP disclosed
JP-H01135737-A PRODUCTION OF (3,3,3,2,2,1,1-HEPTAFLUOROPROPOXY)-METHYLBENZENE NEOS CO LTD 1989-05-29 JP disclosed