Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518490 | 0.85 | SMN1; SMN2 (0.47) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10518957 | 0.80 | KIT (0.48) | NPSR1SMN1; SMN2RAB9AMAPK1KIT | |
| Darenzepine SCHEMBL996265 | 0.79 | MEN1 (0.52) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL379160 | 0.74 | MEN1 (0.76) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL7393652 | 0.74 | MEN1 (0.76) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL4814264 | 0.74 | MEN1 (0.76) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL3970912 | 0.74 | MEN1 (0.76) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL15011579 | 0.73 | MEN1 (0.73) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| Bicarbonate SCHEMBL4357688 | 0.73 | MEN1 (0.73) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL5357397 | 0.72 | SMN1; SMN2 (0.44) | NPSR1MEN1KMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309422-A2 | New amidino tricycle derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |