Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 3/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083981 | 0.81 | MMP2 (0.43) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL21437165 | 0.81 | MMP2 (0.43) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL27732355 | 0.79 | MMP2 (0.36) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL4669194 | 0.79 | MMP2 (0.39) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL2969980 | 0.77 | ELANE (0.40) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL4669111 | 0.76 | KDM4E (0.42) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL14152776 | 0.76 | CCR1 (0.35) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL27732359 | 0.76 | KMT2A (0.37) | KMT2AMEN1MAPTMMP2MMP9 | |
| SCHEMBL20879871 | 0.75 | KMT2A (0.36) | KMT2AMEN1MAPTSLC9A1ALOX5 | |
| Hexane SCHEMBL27754451 | 0.74 | KMT2A (0.47) | KMT2AMEN1MAPTALOX5NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311010-A2 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |