Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526529 | 0.86 | HCAR2 (0.36) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL1681889 | 0.79 | TSHR (0.53) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL17320929 | 0.77 | THRB (0.51) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL28846555 | 0.77 | THRB (0.59) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL704182 | 0.77 | MAPK1 (0.40) | ALDH1A1CYP3A4HIF1ACHRM2CHRM1 | |
| SCHEMBL16491624 | 0.75 | THRB (0.47) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL7880365 | 0.75 | TSHR (0.53) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL3953735 | 0.75 | TSHR (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL27993968 | 0.75 | THRB (0.49) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL15405613 | 0.74 | THRB (0.48) | THRBTSHRHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886852-A | PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION | KANSAI PAINT COMPANY, LIMITED (JP) | 1989-12-12 | — | — | US | claimed |
| US-4886852-A | PREPARING NONAQUEOUS DISPERSION IN ORGANIC SOLVENT, THEN NEUTRALIZATION | KANSAI PAINT COMPANY, LIMITED (JP) | 1989-12-12 | — | — | US | disclosed |