Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | DRD3 | P35462 | 3/20 | 0.71 |
| ▸ | HTR2A | P28223 | 2/20 | 0.71 |
| ▸ | HTR2B | P41595 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | DRD2 | P14416 | 2/20 | 0.71 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.71 |
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | FYN | P06241 | 1/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456714 | 0.89 | HRH1 (0.73) | HRH1KCNH2LMNADRD3HTR2A | |
| Hydrochloric Acid SCHEMBL8454720 | 0.89 | HRH1 (0.74) | HRH1KCNH2LMNADRD3HTR2A | |
| Hydrochloric Acid SCHEMBL8454992 | 0.88 | HRH1 (0.72) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL29120622 | 0.87 | HRH1 (0.64) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL8678278 | 0.84 | HRH1 (0.68) | HRH1KCNH2LMNADRD3HTR2A | |
| Terfenadine SCHEMBL5999024 | 0.83 | KCNH2 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| SCHEMBL11871354 | 0.83 | KCNH2 (0.96) | HRH1KCNH2LMNADRD3HTR2A | |
| R-Terfenadine SCHEMBL155924 | 0.83 | KCNH2 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Terfenadine SCHEMBL5998456 | 0.83 | KCNH2 (1.00) | HRH1KCNH2LMNADRD3HTR2A | |
| Terfenadine SCHEMBL5999023 | 0.83 | KCNH2 (1.00) | HRH1KCNH2LMNADRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1290661-A | — | — | None | — | — | JP | disclosed |
| JP-H01290661-A | PRODUCTION OF POLYMORPHICALLY PURE TERPHENAZINE | MERRELL DOW PHARMACEUT INC | 1989-11-22 | — | — | JP | disclosed |