Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526691 | 1.00 | REN (0.54) | REN | |
| SCHEMBL10524620 | 0.94 | REN (0.54) | REN | |
| SCHEMBL10525394 | 0.88 | REN (0.57) | REN | |
| SCHEMBL10526288 | 0.88 | REN (0.54) | REN | |
| SCHEMBL10980046 | 0.87 | REN (0.60) | REN | |
| SCHEMBL10981774 | 0.87 | REN (0.60) | REN | |
| SCHEMBL10980049 | 0.87 | REN (0.60) | REN | |
| SCHEMBL10525368 | 0.87 | REN (0.51) | REN | |
| SCHEMBL10528201 | 0.86 | REN (0.52) | REN | |
| SCHEMBL10421165 | 0.84 | REN (0.56) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321497-A1 | RENIN INHIBITORY PEPTIDES HAVING NOVEL C-TERMINAL MOIETIES | THE UPJOHN COMPANY (US) | 1989-06-28 | — | — | EP | claimed |
| WO-1988002374-A2 | RENIN INHIBITORY PEPTIDES HAVING NOVEL C-TERMINAL MOIETIES | THE UPJOHN COMPANY (US) | 1988-04-07 | — | — | WO | claimed |
| EP-0321497-A1 | RENIN INHIBITORY PEPTIDES HAVING NOVEL C-TERMINAL MOIETIES | THE UPJOHN COMPANY (US) | 1989-06-28 | — | — | EP | disclosed |
| WO-1988002374-A2 | RENIN INHIBITORY PEPTIDES HAVING NOVEL C-TERMINAL MOIETIES | THE UPJOHN COMPANY (US) | 1988-04-07 | — | — | WO | disclosed |