Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10528580 | 0.99 | KMT2A (0.43) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10528532 | 0.87 | MAPT (0.49) | KMT2ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| Bromide SCHEMBL10526754 | 0.86 | MAPT (0.51) | SMN1; SMN2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL10531137 | 0.80 | KMT2A (0.47) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| Bromide SCHEMBL10529155 | 0.79 | KMT2A (0.49) | KMT2AHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL10529180 | 0.79 | KMT2A (0.45) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| Bromide SCHEMBL10531122 | 0.78 | KMT2A (0.44) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4394987 | 0.76 | KMT2A (0.54) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11044058 | 0.75 | HPGD (0.56) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7913254 | 0.73 | HPGD (0.55) | KMT2AHPGDSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182533-B1 | 3-(2-ARYL-2-OXOETHYL)-IMIDAZOLIUM SALTS AS HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1989-09-20 | — | — | EP | claimed |