Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.42 |
| ▸ | WNT3A | P56704 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10529155 | 0.99 | KMT2A (0.49) | KMT2APABPC1ATMPARP1CTNNB1 | |
| SCHEMBL10528532 | 0.82 | MAPT (0.49) | KMT2APARP1CTNNB1WNT3ATDP1 | |
| SCHEMBL4394987 | 0.82 | KMT2A (0.54) | KMT2APABPC1ATMHPGDTDP1 | |
| Bromide SCHEMBL10526754 | 0.81 | MAPT (0.51) | PARP1CTNNB1WNT3ATDP1HDAC8 | |
| Bromide SCHEMBL10526748 | 0.81 | ALDH1A1 (0.54) | KMT2APABPC1ATMLMNAKDM4E | |
| SCHEMBL10526705 | 0.80 | KMT2A (0.43) | KMT2AHPGDLMNAKDM4EALDH1A1 | |
| Bromide SCHEMBL10528580 | 0.79 | KMT2A (0.43) | KMT2AHPGDLMNAKDM4EALDH1A1 | |
| SCHEMBL10526761 | 0.77 | HSD11B1 (0.42) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10529179 | 0.76 | KMT2A (0.47) | KMT2APABPC1ATMPARP1CTNNB1 | |
| Bromide SCHEMBL10531095 | 0.76 | HSD11B1 (0.41) | KMT2AHPGDLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182533-B1 | 3-(2-ARYL-2-OXOETHYL)-IMIDAZOLIUM SALTS AS HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1989-09-20 | — | — | EP | claimed |