Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735752 | 0.84 | — | — | |
| Bromide SCHEMBL5155661 | 0.81 | — | — | |
| Fluoride SCHEMBL5016225 | 0.81 | — | — | |
| Water SCHEMBL2821935 | 0.81 | — | — | |
| Bicarbonate SCHEMBL28375448 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP2C19TP53HMGCR | |
| Oxalic Acid SCHEMBL1052168 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP2C19TP53HMGCR | |
| Alcohol SCHEMBL14840135 | 0.73 | TSHR (0.38) | ALDH1A1TSHRCYP2C19PIK3CD | |
| SCHEMBL8420027 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP2C19TP53HMGCR | |
| Oxalic Acid SCHEMBL1048771 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP2C19TP53 | |
| SCHEMBL8423443 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP2C19TP53HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867471-B2 | Process for preparing advanced ceramic powders using onium dicarboxylates | SACHEM, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090250850-A1 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDERS USING ONIUM DICARBOXYLATES | SACHEM, INC. | 2009-10-08 | — | — | US | disclosed |