Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL10527770

CCCC[N+](CCCC)(CCCC)CCCC.O=C([O-])C(F)(F)C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.46
SLC22A2 O15244 1/20 0.41
FAAH O00519 8/20 0.39
CES1 P23141 5/20 0.38
CES2 O00748 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL4934068 0.89 SLC22A1 (0.43) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL2184844 0.86 SLC22A1 (0.40) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL9495552 0.86 SLC22A1 (0.40) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL107845 0.86 SLC22A1 (0.52) SLC22A1SLC22A2FAAHCES1CES2
SCHEMBL1701168 0.83 SLC22A1 (0.38) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL7700891 0.83 SLC22A1 (0.38) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL10529094 0.82 SLC22A1 (0.48) SLC22A1SLC22A2FAAHCES1CES2
Tetrapentylammonium SCHEMBL15355495 0.82 SLC22A1 (0.52) SLC22A1SLC22A2FAAHCES1CES2
Tetrahexylammonium SCHEMBL15355454 0.80 SLC22A1 (0.54) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL2350563 0.79 SLC22A1 (0.55) SLC22A1SLC22A2CES1CES2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0158875-B1 CHIRAL-RHODIUM-DIPHOSPHINE COMPLEXES FOR ASYMETRIC HYDROGENATIONS F. HOFFMANN-LA ROCHE AG (CH) 1989-12-13 EP disclosed