Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL4934068

CCCC[N+](CCCC)(CCCC)CCCC.O=C([O-])C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.43
SLC22A2 O15244 1/20 0.38
FAAH O00519 8/20 0.37
CES1 P23141 5/20 0.36
CES2 O00748 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL2184844 0.93 SLC22A1 (0.40) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL9495552 0.93 SLC22A1 (0.40) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL7700891 0.90 SLC22A1 (0.38) SLC22A1SLC22A2FAAHCES1CES2
SCHEMBL1701168 0.90 SLC22A1 (0.38) SLC22A1SLC22A2FAAHCES1CES2
Tetrabuthylammonium SCHEMBL10527770 0.89 SLC22A1 (0.46) SLC22A1SLC22A2FAAHCES1CES2
Cetrimonium SCHEMBL10647447 0.85 DNM1 (0.48) FAAHCES1CES2KMT2A
Tetrabuthylammonium SCHEMBL107845 0.83 SLC22A1 (0.52) SLC22A1SLC22A2FAAHCES1CES2
Tetrapropylammonium SCHEMBL1701184 0.82 THRB (0.41) SLC22A1
Tetrabuthylammonium SCHEMBL10529094 0.79 SLC22A1 (0.48) SLC22A1SLC22A2FAAHCES1CES2
Cetrimonium SCHEMBL10869268 0.79 DNM1 (0.46) FAAHCES1CES2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3452821-A1 VOLATILE ELUENT PREPARATION Board of Regents, The University of Texas System (US) 2019-03-13 EP disclosed
US-10228355-B2 Volatile eluent preparation BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-03-12 US disclosed
WO-2017192229-A1 VOLATILE ELUENT PREPARATION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2017-11-09 WO disclosed
US-20170322188-A1 VOLATILE ELUENT PREPARATION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2017-11-09 US disclosed
US-8795942-B2 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-08-05 US disclosed
US-20080153030-A1 Positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-06-26 US disclosed
CN-1010006-B Asymmetric hydrogenation method and application thereof in preparation of R- -pantolactone HOFFMANN LA ROCHE (CH) 1990-10-17 CN disclosed
EP-0158875-B1 CHIRAL-RHODIUM-DIPHOSPHINE COMPLEXES FOR ASYMETRIC HYDROGENATIONS F. HOFFMANN-LA ROCHE AG (CH) 1989-12-13 EP disclosed
US-4652657-A Chiral rhodium-diphosphine complexes HOFFMANN-LA ROCHE INC. (US) 1987-03-24 US disclosed
CN-85103245-A The preparation of chirality rhodium-diphosphonic complex and the application in asymmetric hydrogenation thereof 1986-12-24 CN disclosed
EP-0158875-A2 Chiral-rhodium-diphosphine complexes for asymetric hydrogenations F. HOFFMANN-LA ROCHE AG (CH) 1985-10-23 EP disclosed