Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.60 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL6163131 | 0.79 | PNP (0.62) | XDHGDAPOLA1PNPCDK1 | |
| SCHEMBL5352883 | 0.79 | XDH (0.67) | XDHGDAPOLA1 | |
| SCHEMBL28415480 | 0.76 | GDA (0.61) | XDHGDAPNP | |
| SCHEMBL5347868 | 0.75 | PNP (0.49) | PNPDAGLA | |
| SCHEMBL8535457 | 0.75 | XDH (1.00) | XDHGDAPOLA1 | |
| SCHEMBL10528227 | 0.75 | DAGLA (0.46) | DAGLA | |
| Hydrochloric Acid SCHEMBL258899 | 0.74 | XDH (0.97) | XDHGDAPOLA1 | |
| SCHEMBL5468655 | 0.74 | CDK1 (0.48) | XDHGDAPOLA1CDK1CCNB1 | |
| SCHEMBL28863081 | 0.74 | CDK1 (0.48) | XDHGDAPOLA1CDK1CCNB1 | |
| SCHEMBL30937356 | 0.74 | PNP (0.57) | XDHGDAPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880782-A | 3'-AZIDO-2',3'-DIDEOXYINOSINE AND RELATED COMPOUNDS FOR AIDS | MAX-PLANCK-GESELLSCHAFT ZUR FOEDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1989-11-14 | — | — | US | disclosed |
| EP-0332626-A1 | COMPOSITIONS FOR TREATING VIRAL INFECTIONS IN HUMANS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1989-09-20 | — | — | EP | disclosed |
| EP-0286825-A2 | Use of 3'-fluro-3' deoxythymidine for the manufacture of a medicament for the treatment of virus infections | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1988-10-19 | — | — | EP | disclosed |