Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.75 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.75 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.70 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.70 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | FBP1 | P09467 | 1/20 | 0.70 |
| ▸ | SRC | P12931 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.70 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.70 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398104 | 0.92 | ENTPD1 (0.74) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL31685855 | 0.92 | SIRT2 (0.75) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL9614573 | 0.92 | SIRT2 (0.75) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL636535 | 0.91 | ENTPD1 (0.75) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL636536 | 0.91 | ENTPD1 (0.75) | ENTPD1TRPM2P2RY1 | |
| SCHEMBL14945956 | 0.91 | SIRT2 (0.76) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL15763588 | 0.91 | SIRT2 (0.76) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL11216469 | 0.91 | SIRT2 (0.73) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL9702452 | 0.90 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL6764984 | 0.90 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346400-A1 | TREATMENT OF MALIGNANT TUMORS WITH 8-CHLOROADENOSINE 3',5'-CYCLIC PHOSPHATE, 8-AMINOADENOSINE 3',5'-CYCLIC PHOSPHATE AND PREPARATION THEREOF | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005647-A1 | TREATMENT OF MALIGNANT TUMORS WITH 8-AMINOADENOSINE 3',5'-CYCLIC PHOSPHATE AND COMBINATIONS OF 8-AMINOADENOSINE 3',5'-CYCLIC PHOSPHATE AND 8-CHLOROADENOSINE 3',5'-CYCLIC PHOSPHATE | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-06-29 | — | — | WO | disclosed |
| WO-1989005648-A1 | TREATMENT OF MALIGNANT TUMORS WITH 8-CHLOROADENOSINE 3',5'-CYCLIC PHOSPHATE, 8-AMINOADENOSINE 3',5'-CYCLIC PHOSPHATE AND PREPARATION THEREOF | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-06-29 | — | — | WO | disclosed |