Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.73 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.73 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.69 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.68 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.68 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.68 |
| ▸ | LDHA | P00338 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 1/20 | 0.68 |
| ▸ | SRC | P12931 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.68 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.68 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.68 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685855 | 0.91 | SIRT2 (0.75) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL10528520 | 0.91 | SIRT2 (0.75) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL9614573 | 0.91 | SIRT2 (0.75) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL14945956 | 0.90 | SIRT2 (0.76) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL15763588 | 0.90 | SIRT2 (0.76) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL20277592 | 0.89 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL20277574 | 0.89 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL6764984 | 0.89 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL4315602 | 0.89 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 | |
| SCHEMBL9702452 | 0.89 | SIRT2 (0.72) | SIRT2SIRT1ENTPD1TRPM2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57011997-A | — | — | None | — | — | JP | disclosed |
| JP-S5711997-A | 8-IODINE-ADENOSINE PHOSPHATE COMPOUND AND ITS PREPARATION | CHUGAI PHARMACEUT CO LTD | 1982-01-21 | — | — | JP | disclosed |