Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 3/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655940 | 1.00 | LMNA (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL6257486 | 0.91 | LMNA (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL6255309 | 0.91 | LMNA (0.39) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL9419491 | 0.90 | — | — | |
| SCHEMBL9543091 | 0.87 | TSHR (0.50) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL10773668 | 0.87 | TSHR (0.50) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL10775700 | 0.87 | TSHR (0.50) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL10774678 | 0.87 | TSHR (0.50) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL5903021 | 0.87 | TSHR (0.50) | LMNADNM1TSHRTHRBOPRM1 | |
| SCHEMBL10775752 | 0.87 | TSHR (0.50) | LMNADNM1TSHRTHRBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149093-B1 | N-GLYCOSYLATED UREAS, CARBAMATES AND THIOCARBAMATES, THEIR PREPARATION METHOD AND THEIR USE | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |
| US-4737488-A | Immune system-stimulating N-glycosylated ureas and carbamates | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-12 | — | — | US | disclosed |
| EP-0149093-A2 | N-glycosylated ureas, carbamates and thiocarbamates, their preparation method and their use | BAYER AG (DE) | 1985-07-24 | — | — | EP | disclosed |