Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10529039 | 0.93 | MAPT (0.46) | HTR2AKCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL10531208 | 0.81 | KCNH2 (0.65) | KCNH2MAPTALDH1A1 | |
| SCHEMBL10896046 | 0.79 | KCNH2 (0.53) | HTR2AKCNH2KDM4EALDH1A1HPGD | |
| Oxalic Acid SCHEMBL11228627 | 0.76 | KCNH2 (0.59) | KCNH2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10530872 | 0.76 | KCNH2 (0.71) | HTR2AKCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL23754735 | 0.75 | HTR2A (0.76) | HTR2AMAPTKDM4EALDH1A1HSD17B10 | |
| Undecane SCHEMBL22346217 | 0.75 | HTR2A (0.76) | HTR2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22346191 | 0.75 | HTR2A (0.69) | HTR2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL25171839 | 0.75 | HTR2A (0.76) | HTR2AMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22346499 | 0.75 | HTR2A (0.76) | HTR2AMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178874-B1 | ALKYLSULFONAMIDOPHENYLALKYLAMINES | ELI LILLY AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4596827-A | Antiarrhythmia agents | ELI LILLY AND COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0178874-A1 | Alkylsulfonamidophenylalkylamines | ELI LILLY AND COMPANY (US) | 1986-04-23 | — | — | EP | disclosed |
| US-4569801-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1986-02-11 | — | — | US | disclosed |