SCHEMBL10530686

SCHEMBL10530686

O=C(O)C(=C\C1=C\CCCCCCCC1)/C1=C/CCCCCCCC1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 3/20 0.43
HDAC4 P56524 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
CTSK P43235 1/20 0.36
CCR2 P41597 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10530698 1.00 HDAC2 (0.43) HDAC2HDAC4HDAC8HDAC6HDAC3
SCHEMBL10530694 1.00 HDAC2 (0.43) HDAC2HDAC4HDAC8HDAC6HDAC3
SCHEMBL300627 0.93 HDAC4 (0.43) HDAC2HDAC4HDAC8HDAC6HDAC3
SCHEMBL93924 0.93 HDAC4 (0.43) HDAC2HDAC4HDAC8HDAC6HDAC3
Ethylene Glycol SCHEMBL5493455 0.87 HDAC4 (0.39) HDAC2HDAC4HDAC8HDAC6HDAC3
Phosphoric Acid SCHEMBL4978498 0.87 HDAC4 (0.42) HDAC2HDAC4HDAC8HDAC6HDAC3
Acrylic Acid SCHEMBL11548398 0.86 HDAC4 (0.38) HDAC2HDAC4HDAC8HDAC6HDAC3
Methacrylic Acid SCHEMBL1453926 0.84 HDAC4 (0.37) HDAC2HDAC4HDAC8HDAC6HDAC3
Acrylamide SCHEMBL17870882 0.83 HDAC4 (0.36) HDAC2HDAC4HDAC8HDAC6HDAC3
SCHEMBL9066614 0.79 HDAC4 (0.37) HDAC2HDAC4HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0153587-B1 ELASTOMERIC THERMOPLASTIC MOULDING COMPOSITION AND ITS PREPARATION BASF Aktiengesellschaft (DE) 1989-07-12 EP disclosed
EP-0153587-A2 Elastomeric thermoplastic moulding composition and its preparation BASF Aktiengesellschaft (DE) 1985-09-04 EP disclosed