Acrylamide

Acrylamide

SCHEMBL17870882

C=CC(N)=O.O=C(O)C(=CC1=CCCC1)C1=CCCC1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
FGFR4 P22455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL11548398 0.91 HDAC4 (0.38) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL300627 0.89 HDAC4 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL93924 0.89 HDAC4 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3
Methacrylic Acid SCHEMBL1453926 0.84 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6HDAC3
Ethylene Glycol SCHEMBL5493455 0.84 HDAC4 (0.39) HDAC4HDAC2HDAC8HDAC6HDAC3
Phosphoric Acid SCHEMBL4978498 0.84 HDAC4 (0.42) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL10530686 0.83 HDAC2 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL10530698 0.83 HDAC2 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL10530694 0.83 HDAC2 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3
Acrylic Acid Ethyl Ester SCHEMBL9618615 0.81 GSTP1 (0.32) HDAC4HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10316126-B2 Impact modifier and a polymer composition comprising the same ROHM AND HAAS COMPANY (US) 2019-06-11 US disclosed
EP-3259291-A1 AN IMPACT MODIFIER AND A POLYMER COMPOSITION COMPRISING THE SAME Rohm and Haas Company (US) 2017-12-27 EP disclosed
US-20170362367-A1 IMPACT MODIFIER AND A POLYMER COMPOSITION COMPRISING THE SAME ROHM AND HAAS COMPANY 2017-12-21 US disclosed
WO-2016106055-A1 AN IMPACT MODIFIER AND A POLYMER COMPOSITION COMPRISING THE SAME ROHM AND HAAS COMPANY (US) 2016-06-30 WO disclosed