Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2994567 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL22604708 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL11950286 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KMT2ARAB9AL3MBTL1TSHR | |
| SCHEMBL21895675 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL21895372 | 0.87 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL21895660 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL18559849 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL21895667 | 0.86 | ALDH1A1 (0.68) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL3294863 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9ATDP1POLB | |
| SCHEMBL21895379 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KMT2ARAB9ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837207-A | Diastereoisomers of n6 -endo-bicyclo[2.2.1]heptyladenosine as antihypertensives with selective action | WARNER-LAMBERT COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0291051-A2 | Individual isomers of endo-bicyclo[2.2.1]heptyl adenosine | WARNER-LAMBERT COMPANY (US) | 1988-11-17 | — | — | EP | disclosed |