Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577533 | 0.88 | AKR1C3 (0.70) | AKR1C3HTTCYP2C9RECQLMEN1 | |
| SCHEMBL2060032 | 0.85 | AKR1C3 (0.53) | AKR1C3HTTCYP2C9RECQLMEN1 | |
| SCHEMBL22091933 | 0.83 | AKR1C3 (0.58) | AKR1C3HTTCYP2C9RECQLMEN1 | |
| SCHEMBL464969 | 0.81 | AKR1C3 (0.64) | AKR1C3HTTRECQLMEN1KMT2A | |
| SCHEMBL12276505 | 0.81 | AKR1C3 (0.64) | AKR1C3HTTRECQLMEN1KMT2A | |
| SCHEMBL522434 | 0.81 | AKR1C3 (0.64) | AKR1C3HTTRECQLMEN1KMT2A | |
| SCHEMBL2060119 | 0.79 | AKR1C3 (0.46) | AKR1C3HTTCYP2C9MEN1KMT2A | |
| SCHEMBL1456939 | 0.78 | AKR1C3 (0.59) | AKR1C3HTTCYP2C9RECQLMEN1 | |
| SCHEMBL186692 | 0.78 | AKR1C3 (0.59) | AKR1C3HTTCYP2C9RECQLLMNA | |
| SCHEMBL5163102 | 0.77 | AKR1C3 (0.54) | AKR1C3HTTCYP2C9RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4857574-A | SMOOTH AND GLOSSY FILM | AKZO NV (NL) | 1989-08-15 | — | — | US | claimed |
| EP-0172589-B1 | DISPERSION OF ADDITION (CO)POLYMERS IN AN ORGANIC LIQUID | AKZO N.V. (NL) | 1988-11-23 | — | — | EP | claimed |
| US-4743643-A | GRAFTING (METHY)STYRENE ONTO BUTADIENE POLYMER, PEROXIDE INITIATOR, COATING | AKZO NV (NL) | 1988-05-10 | — | — | US | claimed |
| EP-0172589-A1 | Dispersion of addition (co)polymers in an organic liquid | AKZO N.V. (NL) | 1986-02-26 | — | — | EP | claimed |
| US-4857574-A | SMOOTH AND GLOSSY FILM | AKZO NV (NL) | 1989-08-15 | — | — | US | disclosed |
| EP-0172589-B1 | DISPERSION OF ADDITION (CO)POLYMERS IN AN ORGANIC LIQUID | AKZO N.V. (NL) | 1988-11-23 | — | — | EP | disclosed |
| US-4743643-A | GRAFTING (METHY)STYRENE ONTO BUTADIENE POLYMER, PEROXIDE INITIATOR, COATING | AKZO NV (NL) | 1988-05-10 | — | — | US | disclosed |
| EP-0172589-A1 | Dispersion of addition (co)polymers in an organic liquid | AKZO N.V. (NL) | 1986-02-26 | — | — | EP | disclosed |