SCHEMBL522434

SCHEMBL522434

COC(=O)/C(C)=C/c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.64
ALDH1A1 P00352 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
DHODH Q02127 1/20 0.50
TRPM8 Q7Z2W7 1/20 0.50
RECQL P46063 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HTT P42858 1/20 0.49
TSHR P16473 1/20 0.48
STAT1 P42224 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12276505 1.00 AKR1C3 (0.64) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL464969 1.00 AKR1C3 (0.64) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL5072384 0.86 MAPT (0.50) AKR1C3ALDH1A1MEN1KMT2AHTT
SCHEMBL5072381 0.86 MAPT (0.50) AKR1C3ALDH1A1MEN1KMT2AHTT
SCHEMBL28489502 0.86 AKR1C3 (0.67) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL17447210 0.85 AKR1C3 (0.60) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL27848450 0.85 AKR1C3 (0.60) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL27383706 0.84 AKR1C3 (0.64) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL27414529 0.84 AKR1C3 (0.64) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL9875130 0.84 AKR1C3 (0.64) AKR1C3ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072151-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF BAYLOR UNIVERSITY (US) 2025-04-03 WO disclosed
US-20250100984-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF BAYLOR UNIVERSITY (US) 2025-03-27 US disclosed
CN-117623924-A Preparation method and application of trisubstituted olefin 苏州新启材料科技有限公司 2024-03-01 CN disclosed
EP-3654077-B1 CIRCULAR POLARIZING PLATE LG CHEMICAL LTD (KR) 2023-02-22 EP disclosed
WO-2022257440-A1 ENCAPSULATION THIN FILM, ENCAPSULATION STRUCTURE FOR OPTOELECTRONIC DEVICE, AND ENCAPSULATION METHOD TCL科技集团股份有限公司 2022-12-15 WO disclosed
CN-110709056-B Aqueous microemulsion 弗门尼舍有限公司 2022-12-13 CN disclosed
CN-114975086-A Method for manufacturing semiconductor device 台湾积体电路制造股份有限公司 2022-08-30 CN disclosed
US-11411206-B2 Circularly polarizing plate LG CHEM, LTD. (KR) 2022-08-09 US disclosed
EP-3654077-A1 CIRCULAR POLARIZING PLATE LG Chem, Ltd. (KR) 2020-05-20 EP disclosed
US-20200136094-A1 CIRCULARLY POLARIZING PLATE SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2020-04-30 US disclosed
US-20100087321-A1 Azolylmethyloxiranes, their use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them BASF SE (DE) 2010-04-08 US disclosed
US-20090270256-A1 Azolylmethyloxiranes, Use Thereof for Controlling Plant Pathogenic Fungi, and Agents Containing the Same BASF SE (DE) 2009-10-29 US disclosed
US-20090203700-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them BASF SE (DE) 2009-08-13 US disclosed
US-20090197929-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds BASF SE (DE) 2009-08-06 US disclosed
EP-1781617-A4 ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION JANSSEN PHARMACEUTICA NV (BE) 2009-06-24 EP disclosed
US-7501510-B2 Thiourea compositions and uses thereof THE UNIVERSITY OF HONG KONG (CN) 2009-03-10 US disclosed
EP-1781617-A2 ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION JANSSEN PHARMACEUTICA N.V. (BE) 2007-05-09 EP disclosed
WO-2006004742-A2 α, β-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION JANSSEN PHARAMCEUTICA N.V. (BE) 2006-01-12 WO disclosed
US-20060004195-A1 Alpha,beta-unsaturated esters and acids by stereoselective dehydration JANSSEN PHARMACEUTICA N.V. (BE) 2006-01-05 US disclosed
US-3936473-A COPPER OR NOBLE METAL SALT, OXYGEN AND ORGANIC ACID CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197929-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi and Agents Containing Said Compounds CBR3, PPOX, CBR1 AKR1C3 12/4885ALDH1A1 465/4885NPC1 2438/4885
US-20250100984-A1 SELECTIVE PARTIAL REDUCTION OF ESTERS USING GROUP IV TRANSITION METAL CATALYSTS AND USES THEREOF ADH1A, ADH5, ADH1C AKR1C3 55/4885ALDH1A1 66/4885NPC1 3519/4885
US-20090203700-A1 Azolylmethyloxiranes, Their Use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them CBR3, NAT1, C5 AKR1C3 11/4885ALDH1A1 725/4885NPC1 3233/4885
US-20060004195-A1 Alpha,beta-unsaturated esters and acids by stereoselective dehydration CCKAR, CCKBR, FFAR1 AKR1C3 229/4885ALDH1A1 597/4885NPC1 1514/4885
US-20100087321-A1 Azolylmethyloxiranes, their use for Controlling Phytopathogenic Fungi, and Compositions Comprising Them PAH, AKR1C4, NAT1 AKR1C3 5/4885ALDH1A1 960/4885NPC1 2386/4885
US-20090270256-A1 Azolylmethyloxiranes, Use Thereof for Controlling Plant Pathogenic Fungi, and Agents Containing the Same NAT1, CBR3, C5 AKR1C3 10/4885ALDH1A1 600/4885NPC1 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.