Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533865 | 1.00 | MAPT (0.50) | MAPTRXFP1GRIK1TRPV1ACHE | |
| SCHEMBL6819969 | 0.98 | GRIK1 (0.51) | MAPTRXFP1GRIK1TRPV1ACHE | |
| SCHEMBL6819963 | 0.98 | GRIK1 (0.51) | MAPTRXFP1GRIK1TRPV1ACHE | |
| SCHEMBL10912747 | 0.86 | GRIK1 (0.64) | GRIK1HDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL6467606 | 0.79 | TBXAS1 (0.52) | MAPTRXFP1TRPV1HDAC1HDAC2 | |
| SCHEMBL6255796 | 0.79 | TBXAS1 (0.52) | MAPTRXFP1TRPV1HDAC1HDAC2 | |
| SCHEMBL1122044 | 0.79 | TBXAS1 (0.52) | MAPTRXFP1TRPV1HDAC1HDAC2 | |
| SCHEMBL343141 | 0.79 | TBXAS1 (0.52) | MAPTRXFP1TRPV1HDAC1HDAC2 | |
| SCHEMBL1122039 | 0.79 | TBXAS1 (0.52) | MAPTRXFP1TRPV1HDAC1HDAC2 | |
| SCHEMBL2967192 | 0.79 | TBXAS1 (0.52) | MAPTRXFP1TRPV1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304139-A1 | Process for making 5-hydroxy-3-hydroxymethyl-2-phenylfuran derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0304138-A1 | Process for making 1,3-dioxane derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |