Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.51 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 4/20 | 0.58 |
| ▸ | FLT4 | P35916 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538852 | 0.94 | FLT1 (0.57) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL3911788 | 0.90 | FLT1 (0.58) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL7767864 | 0.89 | CYP1A2 (0.58) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL29242 | 0.89 | CYP1A2 (0.67) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL2724772 | 0.89 | CYP1A2 (0.67) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL11320631 | 0.89 | CYP1A2 (0.67) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL28180410 | 0.89 | CYP1A2 (0.67) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| Sulfuric Acid SCHEMBL28654341 | 0.89 | CA1 (0.62) | CA1CA2CA12CA3CA4 | |
| Sulfamide SCHEMBL9749647 | 0.87 | CA1 (0.63) | FLT1FLT4KDRCYP1A2CYP2C9 | |
| SCHEMBL7769139 | 0.87 | CYP1A2 (0.56) | FLT1FLT4KDRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712509-A | Cyclic dinucleotides as STING agonists | 詹森生物科技公司 | 2020-09-25 | — | — | CN | disclosed |
| US-4832697-A | Hair dye preparations containing substantive nitrodiphenylamine derivatives | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-05-23 | — | — | US | disclosed |