Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007475 | 0.96 | CYSLTR1 (0.53) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7717069 | 0.92 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7008285 | 0.90 | CYSLTR1 (0.60) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7004658 | 0.87 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7514327 | 0.87 | CYSLTR1 (0.52) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7009755 | 0.86 | CYSLTR1 (0.65) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10534526 | 0.86 | CYSLTR1 (0.45) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7717000 | 0.85 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2 | |
| SCHEMBL7007631 | 0.84 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7516263 | 0.84 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989004305-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |