Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534516 | 0.96 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7008285 | 0.93 | CYSLTR1 (0.60) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7004658 | 0.90 | CYSLTR1 (0.61) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7009755 | 0.89 | CYSLTR1 (0.65) | CYSLTR1GPBAR1CYSLTR2ALOX5 | |
| SCHEMBL10534526 | 0.89 | CYSLTR1 (0.45) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7717069 | 0.88 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7007631 | 0.87 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7715945 | 0.87 | CYSLTR1 (0.56) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10422068 | 0.87 | CYSLTR1 (0.56) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9827674 | 0.87 | CYSLTR1 (0.58) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267874-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | Aventis Pharma Deutschland GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| EP-1030665-A4 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | AVENTIS PHARM PROD INC (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001066098-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | AVENTIS PHARMA DEUTSCHLAND GMBH | 2001-09-13 | — | — | WO | disclosed |
| EP-1030665-A1 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | Aventis Pharmaceuticals Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999020275-A1 | THERAPEUTIC USES OF QUINOLINE DERIVATIVES | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-04-29 | — | — | WO | disclosed |