Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534839 | 1.00 | TSHR (0.35) | TSHRALDH1A1TDP1PLA2G2CSMN1; SMN2 | |
| SCHEMBL10533522 | 0.90 | TSHR (0.36) | TSHRALDH1A1PLA2G2CCYP1A2PKM | |
| SCHEMBL10536790 | 0.89 | TSHR (0.30) | TSHR | |
| SCHEMBL10536786 | 0.89 | TSHR (0.30) | TSHR | |
| SCHEMBL9647107 | 0.87 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9647083 | 0.87 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9647097 | 0.87 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9442422 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1CYP1A2LSS | |
| SCHEMBL9406705 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1CYP1A2LSS | |
| SCHEMBL9442439 | 0.85 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1CYP1A2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011496-A1 | SIDE-CHAIN POLYMERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-30 | — | — | WO | disclosed |