Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535278 | 1.00 | TSHR (0.48) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10534925 | 0.97 | TSHR (0.46) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10536864 | 0.97 | TSHR (0.51) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10532982 | 0.94 | TSHR (0.41) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10533497 | 0.94 | TSHR (0.49) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10535459 | 0.93 | TSHR (0.47) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10533618 | 0.91 | TSHR (0.39) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10534897 | 0.91 | TSHR (0.44) | TSHRHTTMEN1KMT2ANAAA | |
| SCHEMBL10536771 | 0.91 | TSHR (0.47) | TSHRHTTNAAATHRBEPHX2 | |
| SCHEMBL21321819 | 0.91 | TSHR (0.55) | TSHRHTTMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011496-A1 | SIDE-CHAIN POLYMERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-30 | — | — | WO | disclosed |