Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533618 | 0.97 | TSHR (0.39) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10534897 | 0.97 | TSHR (0.44) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10534902 | 0.94 | TSHR (0.48) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10535278 | 0.94 | TSHR (0.48) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10536764 | 0.94 | TSHR (0.42) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10535333 | 0.93 | THRB (0.39) | TSHRTHRBNAAA | |
| SCHEMBL10534925 | 0.91 | TSHR (0.46) | TSHRTHRBNAAAMEN1HTT | |
| SCHEMBL10536864 | 0.91 | TSHR (0.51) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10535459 | 0.90 | TSHR (0.47) | TSHRTHRBNAAAPKMMEN1 | |
| SCHEMBL10534072 | 0.89 | THRB (0.41) | TSHRTHRBNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1989011496-A1 | SIDE-CHAIN POLYMERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-30 | — | — | WO | disclosed |