SCHEMBL10535233

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.62

▸	NPY4R	P50391	8/20	0.54

▸	NPY1R	P25929	5/20	0.54

▸	NPY2R	P49146	4/20	0.54

▸	NPY5R	Q15761	4/20	0.54

▸	KEAP1	Q14145	1/20	0.53

▸	IL23R	Q5VWK5	5/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10535214	1.00	TFPI (0.62)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL30567797	0.93	TFPI (0.62)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL29777861	0.91	TFPI (0.62)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL29974215	0.90	TFPI (0.68)	TFPIKEAP1IL23R
SCHEMBL29512407	0.90	NPY4R (0.58)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL31757517	0.90	NPY4R (0.54)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL30558178	0.88	NPY4R (0.59)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL29430569	0.88	TFPI (0.70)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL8815384	0.88	NPY4R (0.62)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL8813021	0.88	NPY4R (0.62)	TFPINPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1989010416-A1	PROTECTIVE PEPTIDES DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUS-1 gp160	TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US)	1989-11-02	—	—	WO	claimed