SCHEMBL29430569

SCHEMBL29430569

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.70

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.70
▸ NPY4R P50391 9/20 0.59
▸ NPY1R P25929 6/20 0.59
▸ NPY5R Q15761 5/20 0.59
▸ NPY2R P49146 4/20 0.59
▸ VIPR2 P41587 3/20 0.58
▸ VIPR1 P32241 3/20 0.58
▸ IL23R Q5VWK5 1/20 0.57
▸ NPBWR1 P48145 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30385132 0.92 TFPI (0.63) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL30436216 0.89 TFPI (0.79) TFPIVIPR2VIPR1
Mmi-0100 SCHEMBL29380469 0.88 TFPI (0.65) TFPINPY4RNPY1RNPY5RNPY2R
Misgurin SCHEMBL29509599 0.88 TFPI (0.72) TFPIVIPR2VIPR1
SCHEMBL29770069 0.88 TFPI (0.63) TFPIIL23R
SCHEMBL29551264 0.88 TFPI (0.71) TFPIVIPR2VIPR1
SCHEMBL29851163 0.88 TFPI (0.71) TFPIVIPR2VIPR1
SCHEMBL10535233 0.88 TFPI (0.62) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL10535214 0.88 TFPI (0.62) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL30512596 0.88 NPY4R (0.67) TFPINPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673119-A1 PROCESS FOR PREPARATION OF DUAL GIP/GLP-1 PEPTIDES HAVING CONTROLLED PARTICLE SIZE Assia Chemical Industries Ltd. (IL) 2026-01-07 — — EP claimed
WO-2025133045-A1 FERMENTATION PROCESS NOVO NORDISK A/S (DK) 2025-06-26 — — WO claimed
WO-2025133729-A1 PROCESS FOR PREPARATION OF GLP-1 PEPTIDES AND DUAL GLP-1/GIP PEPTIDES HAVING CONTROLLED PARTICLE SIZE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-06-26 — — WO claimed
WO-2024180512-A1 PROCESS FOR PREPARATION OF DUAL GIP/GLP-1 PEPTIDES HAVING CONTROLLED PARTICLE SIZE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2024-09-06 — — WO claimed
EP-4713019-A2 CPG CONJUGATES AND METHODS OF USE The Board of Trustees of the Leland Stanford Junior University (US) 2026-03-25 — — EP disclosed
WO-2026046202-A1 USE OF GLP-1/GIP PEPTIDE OR PHARMACEUTICAL COMPOSITION CONTAINING SAME 博瑞生物医药(苏州)股份有限公司 2026-03-05 — — WO disclosed
WO-2026046202-A1 USE OF GLP-1/GIP PEPTIDE OR PHARMACEUTICAL COMPOSITION CONTAINING SAME 博瑞生物医药(苏州)股份有限公司 2026-03-05 — — WO disclosed
EP-4701649-A1 TREATMENT OF DIABETES MELLITUS Carmot Therapeutics Inc. (US) 2026-03-04 — — EP disclosed
EP-4673119-A1 PROCESS FOR PREPARATION OF DUAL GIP/GLP-1 PEPTIDES HAVING CONTROLLED PARTICLE SIZE Assia Chemical Industries Ltd. (IL) 2026-01-07 — — EP disclosed
US-12492236-B2 Fusion proteins for the treatment of cardiometabolic diseases SHATTUCK LABS, INC. (US) 2025-12-09 — — US disclosed
WO-2025133045-A1 FERMENTATION PROCESS NOVO NORDISK A/S (DK) 2025-06-26 — — WO disclosed
WO-2025133729-A1 PROCESS FOR PREPARATION OF GLP-1 PEPTIDES AND DUAL GLP-1/GIP PEPTIDES HAVING CONTROLLED PARTICLE SIZE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-06-26 — — WO disclosed
WO-2023121699-A1 CYCLIC PEPTIDE FOR CANCER IMMUNOTHERAPY KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2023-06-29 — — WO disclosed
US-11590237-B2 Pharmaceutical formulation comprising incretin-insulin conjugates MERCK SHARP & DOHME LLC (US) 2023-02-28 — — US disclosed
US-11572399-B2 Long-acting GIP peptide analogues UNIVERSITY OF COPENHAGEN (DK) 2023-02-07 — — US disclosed
US-11555057-B2 Compositions and methods for inhibiting tumor cells by inhibiting the transcription factor ATF5 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2023-01-17 — — US disclosed
CN-114761420-A Optimized GIP peptide analogs 安泰博医药 2022-07-15 — — CN disclosed
WO-2022106646-A1 LACTAM AND LACTONE DERIVATIVES OF FORMULA (IA) FOR USE IN THE TREATMENT OF DISEASES CAUSED BY A CORONAVIRUS INFECTION AND/OR A VIRAL RESPIRATORY INFECTION Université Catholique de Louvain (BE) 2022-05-27 — — WO disclosed
EP-4000620-A1 LACTAM AND LACTONE DERIVATIVES FOR USE IN THE TREATMENT OF A VIRAL INFECTION SUCH AS COVID-19 Université catholique de Louvain (BE) 2022-05-25 — — EP disclosed
US-20220073963-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING TYPE 1 DIABETES AND OTHER AUTOIMMUNE DISEASES UNIV JOHNS HOPKINS (US) 2022-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11590237-B2 Pharmaceutical formulation comprising incretin-insulin conjugates IAPP, GLP1R, INSR TFPI 2876/4885NPY4R 92/4885NPY1R 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback