Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180013 | 0.90 | TDP1 (0.44) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL8164447 | 0.86 | TSHR (0.42) | TSHRTDP1GRIK1GRIK2CYP3A4 | |
| SCHEMBL28639365 | 0.83 | GRIK1 (0.38) | TSHRTDP1GRIK1GRIK2CYP3A4 | |
| SCHEMBL2908750 | 0.83 | TSHR (0.47) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28215675 | 0.83 | GRIK1 (0.38) | TSHRTDP1GRIK1GRIK2CYP3A4 | |
| SCHEMBL5368556 | 0.83 | TDP1 (0.40) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 | |
| SCHEMBL28263168 | 0.82 | TSHR (0.59) | TSHRTDP1NPSR1MAPT | |
| SCHEMBL8678914 | 0.81 | TSHR (0.36) | TSHRTDP1CPA1ALDH1A1GAA | |
| SCHEMBL5368563 | 0.80 | TDP1 (0.43) | TSHRTDP1GRIK1GRIK2CYP3A4 | |
| SCHEMBL28662748 | 0.80 | TSHR (0.47) | TSHRTDP1CYP3A4NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145553-A | Synthesis and application of 2, 3-alkyl substituted diester succinate | UNIV DALIAN TECH | 2013-06-12 | — | — | CN | disclosed |
| US-4855378-A | ADHESION PROMOTERS | WACKER-CHEMIE GMBH (DE) | 1989-08-08 | — | — | US | disclosed |