SCHEMBL5368563

SCHEMBL5368563

C=CCOC(=O)CC(CC(=O)OCC=C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
PKM P14618 1/20 0.39
GRIK1 P39086 2/20 0.37
GRIK2 Q13002 2/20 0.37
CYP3A4 P08684 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CPA1 P15085 1/20 0.36
SLC15A1 P46059 2/20 0.36
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
CASP1 P29466 4/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446951 0.94 TDP1 (0.40) TDP1TSHRSMN1; SMN2PKMGRIK1
SCHEMBL180013 0.85 TDP1 (0.44) TDP1TSHRSMN1; SMN2PKMCYP3A4
SCHEMBL28834303 0.83 TDP1 (0.43) TDP1TSHRSMN1; SMN2PKMCYP3A4
SCHEMBL5368556 0.82 TDP1 (0.40) TDP1TSHRSMN1; SMN2PKMCYP3A4
SCHEMBL829459 0.82 SMN1; SMN2 (0.43) TDP1TSHRSMN1; SMN2PKMCYP3A4
SCHEMBL10536244 0.80 TSHR (0.44) TDP1TSHRSMN1; SMN2PKMGRIK1
SCHEMBL12477531 0.80 TDP1 (0.41) TDP1TSHRSMN1; SMN2PKMCYP3A4
SCHEMBL2201794 0.80 GRIK1 (0.47) TDP1TSHRSMN1; SMN2PKMGRIK1
SCHEMBL2201786 0.80 GRIK1 (0.47) TDP1TSHRSMN1; SMN2PKMGRIK1
SCHEMBL16574651 0.80 TDP1 (0.49) TDP1TSHRSMN1; SMN2PKMCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10239963-B2 Mixed salt suspension polymerization process and resins and catalysts produced thereof ROHM AND HAAS COMPANY (US) 2019-03-26 US disclosed
EP-2859021-B1 MIXED SALT SUSPENSION POLYMERIZATION PROCESS AND RESINS AND CATALYSTS PRODUCED THEREOF ROHM & HAAS (US) 2017-02-22 EP disclosed
US-9493585-B2 Polymeric bead composition comprising polymerized phosphorous-containing acid monomer ROHM AD HAAS COMPANY (US) 2016-11-15 US disclosed
US-20150105487-A1 MIXED SALT SUSPENSION POLYMERIZATION PROCESS AND RESINS AND CATALYSTS PRODUCED THEREOF ROHM AND HAAS COMPANY (US) 2015-04-16 US disclosed
EP-2859021-A1 MIXED SALT SUSPENSION POLYMERIZATION PROCESS AND RESINS AND CATALYSTS PRODUCED THEREOF Rohm and Haas Company (US) 2015-04-15 EP disclosed
US-9006365-B2 Method of making polymeric bead from phosphorous acid containing monomers ROHM AND HAAS COMPANY (US) 2015-04-14 US disclosed
WO-2013188221-A1 MIXED SALT SUSPENSION POLYMERIZATION PROCESS AND RESINS AND CATALYSTS PRODUCED THEREOF ROHM AND HAAS COMPANY (US) 2013-12-19 WO disclosed
EP-2471823-B1 New polymeric bead compositions ROHM & HAAS (US) 2013-10-16 EP disclosed
US-20120172561-A1 Method of Making Polymeric Bead From Phosphorous Acid Containing Monomers ROHM AND HAAS COMPANY 2012-07-05 US disclosed
US-20120171489-A1 New Polymeric Bead Compositions ROHM AND HAAS COMPANY 2012-07-05 US disclosed
US-20060073250-A1 Continuous adsorption process for the preparation of a soy protein-containing composition having improved flavor, odor, appearance, or functionality SOLAE, LLC. 2006-04-06 US disclosed
US-20060062889-A1 Soy protein-containing composition SOLAE, LLC. 2006-03-23 US disclosed
EP-0575121-B1 Treatment of food products ROHM & HAAS (US) 1999-03-17 EP disclosed
EP-0604109-B1 Suspension polymerization process for water-soluble monomers ROHM & HAAS (US) 1996-10-02 EP disclosed
US-5498678-A Suspension polymerization process for water-soluble monomers ROHM AND HAAS COMPANY (US) 1996-03-12 US disclosed
EP-0604109-A2 Suspension polymerization process for water-soluble monomers ROHM AND HAAS COMPANY (US) 1994-06-29 EP disclosed
EP-0361685-B1 Ion exchange resins ROHM & HAAS (US) 1994-01-19 EP disclosed
EP-0575121-A1 Treatment of food products and by-products ROHM AND HAAS COMPANY (US) 1993-12-22 EP disclosed
EP-0556879-A2 Ion exchange resins ROHM AND HAAS COMPANY (US) 1993-08-25 EP disclosed
EP-0361685-A1 Ion exchange resins ROHM AND HAAS COMPANY (US) 1990-04-04 EP disclosed