Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534982 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536739 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536845 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536837 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536762 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536807 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10783104 | 0.98 | HSD11B1 (0.37) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536571 | 0.90 | HSD11B1 (0.32) | TSHRHSD11B1HSD11B2CCR2 | |
| SCHEMBL10787187 | 0.90 | TSHR (0.47) | TSHRTHRBHSD11B1HSD11B2 | |
| SCHEMBL10783825 | 0.87 | TSHR (0.41) | TSHRTHRBHSD11B1HSD11B2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4867904-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-19 | — | — | US | disclosed |