Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955085 | 0.93 | TSHR (0.33) | TSHRALDH1A1LPAR3LPAR2 | |
| SCHEMBL5430725 | 0.92 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| SCHEMBL534005 | 0.90 | TSHR (0.38) | TSHRALDH1A1LPAR3LPAR2 | |
| SCHEMBL2286811 | 0.90 | TSHR (0.38) | TSHRALDH1A1LPAR3LPAR2 | |
| SCHEMBL27581419 | 0.90 | ALDH1A1 (0.33) | TSHRALDH1A1LPAR3LPAR2 | |
| SCHEMBL5683010 | 0.90 | — | — | |
| SCHEMBL5433844 | 0.90 | — | — | |
| SCHEMBL874849 | 0.88 | MEN1 (0.41) | TSHRLPAR3LPAR2MEN1KMT2A | |
| SCHEMBL5442746 | 0.88 | — | — | |
| SCHEMBL5435527 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843180-A | Preparation of ethers | THE DOW CHEMICAL COMPANY (US) | 1989-06-27 | — | — | US | disclosed |