Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536831 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536757 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536732 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10534979 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536835 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536612 | 1.00 | TSHR (0.38) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10536563 | 0.90 | HSD11B1 (0.32) | TSHRHSD11B1HSD11B2 | |
| SCHEMBL10787187 | 0.90 | TSHR (0.47) | TSHRTHRBHSD11B1HSD11B2DNM1 | |
| SCHEMBL10783825 | 0.87 | TSHR (0.41) | TSHRTHRBHSD11B1HSD11B2CCR2 | |
| SCHEMBL10782756 | 0.82 | HSD11B1 (0.39) | TSHRTHRBHSD11B1HSD11B2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4867904-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-19 | — | — | US | disclosed |