Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.78 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.78 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.78 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503572 | 0.93 | OPRD1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL25330324 | 0.93 | OPRD1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL29392212 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL15757784 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL16922138 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL14611951 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL15653227 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL14516212 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL24971 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Ethylmorphine SCHEMBL18770594 | 0.93 | OPRD1 (0.80) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4795813-A | Synthesis of derivatives of codeine and other 3-O-alkylmorphines | THE FLORIDA BOARD OF REGENTS ON BEHALF OF THE FLORIDA STATE UNIVERSITY (US) | 1989-01-03 | — | — | US | disclosed |
| US-4472253-A | Process for the preparation of an N-substituted 3-O-alkyl-14-hydroxynormorphinone derivative | THE FLORIDA BOARD OF REGENTS ON BEHALF OF THE FLORIDA STATE UNIVERSITY (US) | 1984-09-18 | — | — | US | disclosed |