Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10540683 | 0.92 | MAPT (0.55) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10539603 | 0.88 | MRGPRX1 (0.48) | DRD2ADRA1DADRA1AADRA1BHTR3A | |
| SCHEMBL10539974 | 0.87 | MAPT (0.56) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10540979 | 0.87 | TSHR (0.59) | KMT2AMEN1ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL10538812 | 0.86 | KMT2A (0.51) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10755457 | 0.86 | KMT2A (0.69) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10542205 | 0.86 | POLB (0.60) | KMT2AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL10541801 | 0.85 | KMT2A (0.50) | KMT2AMEN1ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL10542169 | 0.85 | KMT2A (0.68) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL10541780 | 0.85 | CYP2D6 (0.54) | KMT2AMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235878-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1987-09-09 | — | — | EP | claimed |
| US-4797387-A | ANALGESICS, ANTIEMETICS | BEECHAM GROUP, P.L.C. (GB) | 1989-01-10 | — | — | US | disclosed |
| EP-0235878-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1987-09-09 | — | — | EP | disclosed |