Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10539974 | 0.88 | MAPT (0.56) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10755457 | 0.87 | KMT2A (0.69) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10538812 | 0.87 | KMT2A (0.51) | TSHRKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10537855 | 0.87 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL10541780 | 0.86 | CYP2D6 (0.54) | TSHRKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10541801 | 0.86 | KMT2A (0.50) | TSHRKMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10542169 | 0.86 | KMT2A (0.68) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10754148 | 0.84 | KMT2A (0.56) | L3MBTL1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10542188 | 0.84 | PYGL (0.48) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL10542205 | 0.84 | POLB (0.60) | KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235878-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1987-09-09 | — | — | EP | claimed |
| US-4797387-A | ANALGESICS, ANTIEMETICS | BEECHAM GROUP, P.L.C. (GB) | 1989-01-10 | — | — | US | disclosed |
| EP-0235878-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1987-09-09 | — | — | EP | disclosed |