SCHEMBL10537899

SCHEMBL10537899

CCCCC(C)[C@H](CC[C@H]1C(OC2CCCCO2)C[C@H](O)[C@@H]1CCCCCCC(=O)O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGFR P43088 17/20 0.42
PTGER2 P43116 3/20 0.42
TBXA2R P21731 2/20 0.42
ALDH1A1 P00352 1/20 0.38
PTGER1 P34995 9/20 0.34
PTGER3 P43115 2/20 0.34
PTGDR Q13258 1/20 0.34
TBXAS1 P24557 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10538424 1.00 PTGFR (0.42) PTGFRPTGER2TBXA2RALDH1A1PTGER1
SCHEMBL10539802 0.98 PTGFR (0.46) PTGFRPTGER2TBXA2RALDH1A1PTGER1
SCHEMBL10538754 0.89 MEN1 (0.41) PTGFRTBXA2RALDH1A1PTGER1PTGER3
SCHEMBL10536458 0.89 MEN1 (0.41) PTGFRTBXA2RALDH1A1PTGER1PTGER3
SCHEMBL10536200 0.88 PTGFR (0.47) PTGFRPTGER2TBXA2RALDH1A1PTGER1
SCHEMBL10538124 0.88 PTGFR (0.47) PTGFRPTGER2TBXA2RALDH1A1PTGER1
SCHEMBL10538986 0.88 PTGFR (0.47) PTGFRPTGER2TBXA2RALDH1A1PTGER1
SCHEMBL10540664 0.86 MEN1 (0.44) PTGFRTBXA2RALDH1A1PTGER1PTGER3
SCHEMBL10539007 0.86 MEN1 (0.44) PTGFRTBXA2RALDH1A1PTGER1PTGER3
SCHEMBL10536389 0.86 PTGFR (0.33) PTGFRPTGER2TBXA2RALDH1A1PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4888358-A 13,14-dihydroprostaglandin C-type derivatives SYNTEX (U.S.A.) INC. (US) 1989-12-19 US disclosed