Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Methylethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylethylamine SCHEMBL5288733 | 1.00 | — | — | |
| Methylethylamine SCHEMBL14666 | 0.94 | — | — | |
| Methylethylamine SCHEMBL7752889 | 0.89 | — | — | |
| Methylethylamine SCHEMBL21352603 | 0.89 | — | — | |
| Methylethylamine SCHEMBL19358922 | 0.89 | — | — | |
| Methylethylamine SCHEMBL23451683 | 0.89 | — | — | |
| Methylethylamine SCHEMBL20584249 | 0.89 | TP53 (0.42) | — | |
| Methylethylamine SCHEMBL20507023 | 0.89 | — | — | |
| Methylethylamine SCHEMBL21404234 | 0.89 | — | — | |
| Methylethylamine SCHEMBL5688559 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798830-A | TETRAHYDROQUINOLINE DERIVATIVES | RESEARCH CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4634709-A | PIPERIDINE DERIVATIVES | RESEARCH CORPORATION (US) | 1987-01-06 | — | — | US | disclosed |
| US-4443450-A | N,N*-BIS(NIPECOTYL) PIPERAZINE | RESEARCH CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |