Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619199 | 0.82 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL8061638 | 0.76 | LMNA (0.54) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL11257741 | 0.76 | LMNA (0.48) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL11249081 | 0.76 | LMNA (0.48) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL14438979 | 0.72 | PDE4A (0.78) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL8061227 | 0.71 | LMNA (0.48) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL11254098 | 0.70 | NPC1 (0.49) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL11261008 | 0.70 | LMNA (0.42) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL11251263 | 0.70 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 | |
| SCHEMBL9387084 | 0.70 | LMNA (1.00) | LMNASMN1; SMN2MAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873291-A | AND A MORPHOLIN POLYSULFIDE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| US-4808666-A | MORPHOLINE POLYSULFIDES AND DITHIOCARBAMYLTRIAZINES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0282434-A1 | Rubber vulcanization system | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4755320-A | Containing morpholine polysulfide, dithiocarbamyl triazine, sulfur | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |