Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320598 | 0.82 | KCNA5 (0.46) | KCNA5AOC3KDM4EALDH1A1MEN1 | |
| SCHEMBL8907881 | 0.82 | KCNA5 (0.46) | KCNA5AOC3KDM4EALDH1A1MEN1 | |
| SCHEMBL14663983 | 0.82 | KCNA5 (0.46) | KCNA5AOC3KDM4EALDH1A1MEN1 | |
| SCHEMBL11861099 | 0.78 | KDM4E (0.46) | KCNA5AOC3KDM4EALDH1A1MEN1 | |
| SCHEMBL11261712 | 0.76 | KCNA5 (0.43) | KCNA5AOC3KDM4EALDH1A1SLC6A2 | |
| SCHEMBL17076396 | 0.75 | ATM (0.40) | KCNA5AOC3KDM4EMEN1KMT2A | |
| SCHEMBL17076397 | 0.75 | ATM (0.40) | KCNA5AOC3KDM4EMEN1KMT2A | |
| SCHEMBL6579332 | 0.75 | KCNA5 (0.45) | KCNA5AOC3KDM4EALDH1A1MEN1 | |
| SCHEMBL6579342 | 0.75 | KCNA5 (0.45) | KCNA5AOC3KDM4EALDH1A1MEN1 | |
| SCHEMBL7995729 | 0.75 | KCNA5 (0.53) | KCNA5AOC3KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845272-A | Process for the optical resolution of (±)-cis or (±)-trans-permethric acid | KURARAY CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4327038-A | Method for preparing optically active 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0034428-A2 | A method of resolving optical isomers of 2,2-dimethyl-3-(2,2-dichlorovinyl) cyclopropanecarboxylic acid and a novel salt used in this method | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-08-26 | — | — | EP | disclosed |
| US-4229593-A | Method to prepare (+)-cis-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid | FMC CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |