Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10541216 | 0.93 | KMT2A (0.69) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10540209 | 0.90 | KMT2A (0.60) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10542211 | 0.90 | KMT2A (0.60) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10540283 | 0.88 | KMT2A (0.58) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10541405 | 0.86 | KMT2A (0.61) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10538162 | 0.86 | KMT2A (0.56) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL10824127 | 0.84 | DRD2 (0.64) | KMT2AKDM4EALDH1A1CYP2J2DRD2 | |
| SCHEMBL10538477 | 0.83 | KMT2A (0.54) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10540175 | 0.83 | KMT2A (0.58) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL10539191 | 0.82 | KMT2A (0.54) | KMT2AMEN1CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346367-A1 | ARYL- AND ARYLOXY-SUBSTITUTED TERT.-ALKYLENAMINES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN PHARMACY | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-12-20 | — | — | EP | disclosed |
| WO-1988006580-A1 | ARYL- AND ARYLOXY-SUBSTITUTED TERT.-ALKYLENAMINES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN PHARMACY | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-09-07 | — | — | WO | disclosed |