Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 16/20 | 0.48 |
| ▸ | RARB | P10826 | 16/20 | 0.48 |
| ▸ | RARG | P13631 | 15/20 | 0.48 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856383 | 0.89 | RARA (0.46) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL9856391 | 0.83 | RARA (0.49) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL10541102 | 0.81 | RARA (0.56) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL10541995 | 0.77 | RARA (0.46) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL10541085 | 0.77 | RARA (0.49) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9856299 | 0.77 | RARB (0.56) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9856598 | 0.76 | RARA (0.44) | RARARARBRARGRXRAABCB1 | |
| SCHEMBL9856398 | 0.76 | RARB (0.62) | RARARARBRARGRXRAABCB1 | |
| Methane SCHEMBL9856408 | 0.74 | ESR1 (0.57) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL10834806 | 0.73 | RARG (0.50) | RARARARBRARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886907-A | TREATMENT OF DERMATOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-12-12 | — | — | US | disclosed |