SCHEMBL105422

SCHEMBL105422

Nc1ccc(Br)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549225 1.00
Bromide SCHEMBL27819502 0.97
Hydrochloric Acid SCHEMBL6901300 0.97
Cyanide SCHEMBL28309094 0.93 NOS3 (0.44)
Methylene Chloride SCHEMBL27519891 0.91 NOS3 (0.43)
SCHEMBL23361698 0.89 NOS3 (0.46)
Alcohol SCHEMBL28867069 0.87 GBA1 (0.46)
Formic Acid SCHEMBL27975615 0.87 HDAC1 (0.44)
Acetic Acid SCHEMBL28106685 0.85 KDM4E (0.52)
SCHEMBL28230858 0.83 GBA1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6621 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432148-A Perovskite ink, perovskite film and battery device 云南大学 2025-02-14 CN claimed
CN-119281138-A Core-shell structure porous polymer-carbon nano tube filter membrane and preparation method thereof 国能神东煤炭集团有限责任公司 2025-01-10 CN claimed
CN-119264039-A Synthesis method of pyridine drug intermediate 苏州翔实医药发展有限公司 2025-01-07 CN claimed
CN-119264040-A Preparation method of 2,5 pyridine compound 苏州翔实医药发展有限公司 2025-01-07 CN claimed
CN-119034263-A Preparation method of efficient silica gel monolithic column for refining 2-amino-5-bromopyridine 丹阳恒安化学科技研究所有限公司 2024-11-29 CN claimed
CN-118580217-A Preparation method of 4- (6-aminopyridine-3-yl) piperidine-1-tert-butyl formate 甘肃智资医药有限公司 2024-09-03 CN claimed
CN-114874187-B Preparation method of vitamin E 江苏慧聚药业股份有限公司 2024-08-13 CN claimed
CN-115417869-B Synthesis method of 6-bromoimidazole [1.2A ] pyridine-3-formamide 安徽大学 2024-06-11 CN claimed
CN-117964621-A Imidazopyridine derivative and preparation method and application thereof 河北科技大学 2024-05-03 CN claimed
CN-117964622-A Novel isoxazole compound and preparation method and application thereof 河北科技大学 2024-05-03 CN claimed
US-6225009-B1 Electrochemical cell with a non-liquid electrolyte E.C.R. -ELECTRO-CHEMICAL RESEARCH LTD. (IL) 2001-05-01 US claimed
EP-0573878-B1 3-fluoropyridines, process for their preparation and their use in liquid crystal mixtures AVENTIS RES & TECH GMBH & CO (DE) 2000-12-20 EP claimed
EP-0868756-A1 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-10-07 EP claimed
WO-1998013887-A1 ELECTROCHEMICAL CELL WITH A NON-LIQUID ELECTROLYTE E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-04-02 WO claimed
US-5731105-A Battery electrochemical cell with a non-liquid electrolyte E.C.R. - ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1998-03-24 US claimed
US-5580681-A SOLID ELECTROLYTE, ORGANIC ANODE, SOLID CATHODE E.C.R.-ELECTRO-CHEMICAL RESEARCH LTD. (IL) 1996-12-03 US claimed
CN-1082028-A 3-fluorine pyridine, its preparation method and the application in liquid crystal compound HOECHST AG (DE) 1994-02-16 CN claimed
WO-1993025529-A1 3-FLUOROPYRIDINES, METHOD OF PREPARING THEM AND THEIR USE IN LIQUID-CRYSTAL MIXTURES HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-23 WO claimed
WO-1993025530-A2 VINYL ARENAS HAVING RETINOID-LIKE ACTIVITY ALLERGAN, INC. (US) 1993-12-23 WO claimed
EP-0573878-A1 3-fluoropyridines, process for their preparation and their use in liquid crystal mixtures HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-15 EP claimed