Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544127 | 1.00 | POLB (0.37) | POLBTDP1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL10544141 | 1.00 | POLB (0.37) | POLBTDP1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL10811590 | 0.87 | ALDH1A1 (0.36) | POLBTDP1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL10544858 | 0.86 | POLB (0.36) | POLBTDP1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL10683037 | 0.85 | MAPT (0.44) | POLBTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL10663407 | 0.85 | MAPT (0.44) | POLBTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL11455918 | 0.85 | MAPT (0.44) | POLBTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL10683033 | 0.85 | MAPT (0.44) | POLBTDP1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL9661414 | 0.82 | MAPT (0.41) | POLBTDP1L3MBTL1CRHBPCRHR2 | |
| SCHEMBL9661405 | 0.82 | MAPT (0.41) | POLBTDP1L3MBTL1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822788-A | MICROBIOCIDES, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4822790-A | ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4725591-A | USED WITH AMINO ACID DERIVATIVE ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| US-4675397-A | MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-06-23 | — | — | US | disclosed |
| US-4665067-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4550105-A | BETA-LACTAMASE INHIBITORS, ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-29 | — | — | US | disclosed |