Phthalic Acid

Phthalic Acid

SCHEMBL10544697

CCC(O)CCCO.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
ALOX15 P16050 1/20 0.47
POLB P06746 1/20 0.43
KDM4E B2RXH2 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
RECQL P46063 1/20 0.42
HTT P42858 1/20 0.42
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
TSHR P16473 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
AKR1C3 P42330 1/20 0.39
BRS3 P32247 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL5052086 0.89 ALDH1A1 (0.50) ALDH1A1ALOX15POLBKDM4EMEN1
Benzoic Acid SCHEMBL27623024 0.87 DAO (0.47) ALDH1A1HTTLMNAGAAPKM
Phthalic Acid SCHEMBL16702148 0.87 ALDH1A1 (0.58) ALDH1A1ALOX15POLBKDM4EMEN1
Phthalic Acid SCHEMBL8577512 0.84 ALDH1A1 (0.61) ALDH1A1ALOX15POLBKDM4EMEN1
Benzoic Acid SCHEMBL27899369 0.82 DAO (0.45) ALDH1A1HTTLMNAGAAPKM
Phthalic Acid SCHEMBL8576272 0.81 ALDH1A1 (0.55) ALDH1A1ALOX15POLBKDM4EMEN1
Toluic Acid SCHEMBL31280949 0.81 MYC (0.42) ALDH1A1ALOX15POLBKDM4EMEN1
SCHEMBL28724476 0.80 TSHR (0.58) ALDH1A1POLBKDM4ELMNATDP1
SCHEMBL1073056 0.80 HPGD (0.40) ALDH1A1ALOX15POLBKDM4EMEN1
SCHEMBL28377806 0.79 FOLH1 (0.52) ALDH1A1ALOX15KDM4EKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4801632-A Cellulose ester moulding materials with improved toughness BAYER AKTEINGESELLSCHAFT (DE) 1989-01-31 US disclosed
US-4427809-A Thermoplastic moulding compositions of co-graft polymers BAYER AKTIENGESELLSCHAFT (DE) 1984-01-24 US disclosed
US-4368292-A ACRYLIC ESTER, VINYL ESTER; TOUGHNESS, FLEXIBILITY BAYER AKTIENGESELLSCHAFT (DE) 1983-01-11 US disclosed
US-4360635-A Thermoplastic moulding compositions of cellulose ester graft copolymers or mixtures thereof with cellulose esters BAYER AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
US-4357267-A ETHYLENE-VINYL ESTER COPOLYMER BAYER AKTIENGESELLSCHAFT (DE) 1982-11-02 US disclosed