Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 17/20 | 0.52 |
| ▸ | PTGIS | Q16647 | 4/20 | 0.49 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544424 | 0.87 | TBXA2R (0.71) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12329694 | 0.87 | TBXA2R (0.54) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10540544 | 0.85 | TBXAS1 (0.65) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2934087 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12329914 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1897768 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2934089 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2941082 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2940115 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1895403 | 0.84 | TBXA2R (0.76) | TBXA2RMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822815-A | ANTAGONIZING ACTIONS OF THROMBOXANE A2 | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-04-18 | — | — | US | disclosed |
| EP-0228887-A2 | Dioxane hexenoic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-15 | — | — | EP | disclosed |