Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.46 |
| ▸ | PDXK | O00764 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.46 |
| ▸ | STK16 | O75716 | 1/20 | 0.46 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | OXSR1 | O95747 | 1/20 | 0.46 |
| ▸ | LATS1 | O95835 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548598 | 0.85 | MEN1 (0.53) | PIK3CGPOLBHSD17B10MEN1KMT2A | |
| SCHEMBL10543210 | 0.80 | PIK3CG (0.55) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL10544551 | 0.78 | PIK3CG (0.50) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL10546362 | 0.76 | PIK3CG (0.51) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL10546618 | 0.75 | PIK3CG (0.61) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL23064051 | 0.71 | PIK3CG (0.75) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL10543488 | 0.69 | PIK3CG (0.73) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL13019167 | 0.68 | PIK3CG (0.56) | PIK3CGPIK3CACSNK2A2MTORPIK3CD | |
| SCHEMBL10542372 | 0.67 | PIK3CG (0.63) | PIK3CGCSNK2A2CLK1DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL3745102 | 0.67 | PIK3CG (0.55) | PIK3CGPIK3CACSNK2A2MTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4797467-A | COPOLYMERS WITH AROMATIC DIOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-01-10 | — | — | US | disclosed |
| US-4739058-A | USED IN BRANCHED POLYCARBONATES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-19 | — | — | US | disclosed |
| EP-0207413-A1 | Tetra(hydroxyaryl)-bis-quinoxalines, their preparation and their use as branching agents in thermoplastic polycarbonates | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |